膜心脏病对沙尔科病的临床结果的影响
Bilal Hussain1, Favour Markson2, Mamas A Mamas3
1Internal Medicine, The Brooklyn Hospital Center, Brooklyn, NY.
Current problems in cardiology
|June 10, 2023
概括
系统性sarcoidosis患者有5%的发病率的膜心脏病 (VHD),主要影响和大动脉门. 这种并发症与更糟糕的结果有关,包括增加死亡率和更高的住院费用.
科学领域:
- 心脏病学 心脏病学
- 肺部病理学 肺部病理学
- 内部医学 内部医学
背景情况:
- 系统性沙尔科毒症通常会影响心脏,导致心律失常和心力衰竭.
- 关于膜性心脏病 (VHD) 在型硬化症患者的同时发生的数据有限.
- 了解VHD患病率和对型硬化症的影响对于患者管理至关重要.
研究的目的:
- 为了确定VHD的患病率在病人住院治疗的系统性沙尔科发症.
- 在这个患者群体中调查与VHD相关的结果.
- 为了比较VHD管理和成本,在肉类发病患者和没有肉类发病患者.
主要方法:
- 使用2016-2020年国家住院样本 (NIS) 数据库进行的回顾性队列研究.
- 使用相关的ICD-10-CM代码,包括患有沙尔科病的患者.
- 对人口统计数据,VHD流行,死亡率,住院费用和干预率的分析.
主要成果:
- 总共分析了406,315例型硬化症住院病例,其中20,570例 (5.1%) 患有并发性VHD.
- 中心门疾病是最常见的 (2.5%),其次是大动脉和三管门疾病.
- 三病显著增加了死亡率 (OR 1.6),而大动脉疾病在31-50岁的年龄组有所增加. 患有沙丘病和VHD的患者支付的费用更高,干预率相似或更低.
结论:
- 膜性心脏病影响了大约5%的住院的沙尔科毒症患者,主要涉及心肌和大动脉.
- 伴随性VHD与类发病的较差结果有关,包括死亡率增加.
- 需要对沙尔科毒症中VHD的机制和管理进行进一步的研究.
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