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Updated: Jul 27, 2025

Anaerobic Protein Purification and Kinetic Analysis via Oxygen Electrode for Studying DesB Dioxygenase Activity and Inhibition
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Anaerobic Protein Purification and Kinetic Analysis via Oxygen Electrode for Studying DesB Dioxygenase Activity and Inhibition

Published on: October 3, 2018

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人类的胺-2,3-二氧化酶2辅因子可变性和较低的基质亲和力通过同质模型,分子动力学和分子对接来解释

Manon Mirgaux1, Laurence Leherte1, Johan Wouters1

  • 1Department of Chemistry, Laboratoire de Chimie Biologique Structurale (CBS), Namur Institute of Structured Matter (NISM), Namur Research Institute for Life Science (NARILIS), University of Namur (UNamur), Namur, Belgium.

Journal of biomolecular structure & dynamics
|June 10, 2023
PubMed
概括

由于辅因子的不稳定性和基质的不良定位,人类的英多胺-2,3-二氧化酶2 (hIDO2) 蛋白活性尚不清楚. 计算研究表明,这些因素可能解释了hIDO2的存在.

关键词:
同性学建模的模拟.在L-Tryptophan中使用.二氧化碳基因酶的使用.它们是hIDO2和hIDO2.分子对接的分子对接.分子动力学分子动力学

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