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Updated: Jul 27, 2025

Optimized Interferon-gamma ELISpot Assay to Measure T Cell Responses in the Guinea Pig Model after Vaccination
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疫苗诱导的对SARS-CoV-2的保护需要IFN-γ驱动的细胞免疫反应

Xiaolei Wang1,2, Terrence Tsz-Tai Yuen3, Ying Dou1

  • 1School of Biomedical Sciences, Li Ka Shing Faculty of Medicine, The University of Hong Kong, Pokfulam, Hong Kong Special Administrative Region, People's Republic of China.

Nature communications
|June 10, 2023
PubMed
概括

通过诱导细胞免疫力,mRNA疫苗BNT162b2提供了对COVID-19变体的保护. 这种以干扰素-生产为标志的细胞免疫力,在抗体免疫力被规避时,对保护至关重要.

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