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突然听力损失和早期高压氧气疗法:一项初步研究

Mirko Aldè^1,2, Giovanna Cantarella^1,3, Gioia Piatti⁴

¹Department of Clinical Sciences and Community Health, University of Milan, Milan, Italy.

Undersea & hyperbaric medicine : journal of the Undersea and Hyperbaric Medical Society, Inc

|June 11, 2023

概括

高压氧气 (HBO2) 疗法可以改善突然神经感官听力损失 (SSNHL) 患者的听力. 在症状出现后三天内,早期的HBO2治疗在没有类固醇的71.4%的患者中显示出显著的听力恢复.

科学领域:

耳鼻喉科耳鼻喉科耳鼻喉科
高压医学高压医学
听力学听力学是指听力学.

背景情况:

突然感觉神经听力损失 (SSNHL) 是一种迫切需要及时干预的紧急情况.
像皮质类固醇这样的传统治疗方法有局限性和潜在的副作用.
研究SSNHL的替代或辅助疗法至关重要.

研究的目的:

评估仅用高压氧 (HBO2) 治疗的异常性SSNHL患者的听力改善.
评估早期HBO2干预 (72小时内) 作为主要治疗的疗效.
为了确定对皮质类固醇有禁忌或厌恶的患者的听力恢复率.

主要方法:

对2012年至2021年间被诊断患有异常性SSNHL的成年患者的回顾性图表审查.
纳入标准:SSNHL诊断,在72小时内开始HBO2治疗,不使用皮质类固醇.
HBO2协议:至少10次会议,每次85分钟,2.5 ATA压力与纯氧.

主要成果:

49名患者 (平均年龄为47岁) 符合标准.
从69.8dB到31.4dB (p<0.001) 的平均听力值显著改善.
在71.4% (35/49) 的患者中观察到完整的听力恢复.

结论:

早期的HBO2治疗 (3天内) 显示出对异常性SSNHL的积极影响.
这表明HBO2可能是一个有效的独立治疗,当类固醇是禁忌或避免.
进一步的研究可以验证HBO2作为SSNHL的主要治疗选择.

关键词:

听力恢复听力恢复高压氧气疗法 (hyperbaric oxygen therapy) 是一种高压氧气疗法.突然的感觉神经神经听力损失.耳声 (tinnitus) 是一种耳声.

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