睡眠质量差,失眠和感染前睡眠时间短,预测COVID-19后的长期症状
Federico Salfi1, Giulia Amicucci2, Domenico Corigliano2
1Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Brain, behavior, and immunity
|June 11, 2023
概括
感染前睡眠质量差和失眠增加了长期COVID症状的风险. 解决睡眠健康问题可能有助于缓解COVID-19后的疾病,并改善恢复时间.
科学领域:
- 睡眠医学 睡眠医学
- 传染性疾病 传染性疾病
- 公共卫生 公共卫生
背景情况:
- 数以百万计的COVID-19幸存者报告持续的长期症状,这给公共卫生带来了重大挑战.
- 识别COVID-19后疾病的危险因素对于有效的管理和预防至关重要.
- 这项研究调查了感染前睡眠对长期COVID-19症状发展的影响.
研究的目的:
- 评估感染前睡眠质量,睡眠持续时间和失眠严重程度与COVID-19后症状发生率之间的关联.
- 要确定SARS-CoV-2感染前睡眠不足是否预测了长期症状的数量和类型.
- 评估基线睡眠特征与COVID-19的恢复时间之间的关系.
主要方法:
- 一项前性研究,包括基线 (2020年4月) 和后续 (2022年4月) 评估.
- 使用匹兹堡睡眠质量指数 (PSQI) 和失眠严重程度指数 (ISI) 测量睡眠质量/持续时间和失眠.
- COVID-19幸存者 (n=713在1个月,n=333在3个月) 追溯报告了21种长期症状和恢复时间.
主要成果:
- 感染前的睡眠质量,持续时间和失眠严重程度显著影响了COVID-19后1个月和3个月的症状数量.
- 较高的PSQI和ISI得分以及更短的睡眠时间与几乎所有长期症状的风险增加有关.
- 基本睡眠不足与更长的恢复期有关,以恢复感染前的日常功能.
结论:
- 在感染前睡眠健康和COVID-19后症状的表现之间存在潜在的,剂量依赖的关联.
- 积极促进睡眠健康可能是一个可行的策略,以减轻COVID-19的后果.
- 进一步的研究是必要的,以证实这些发现,并探索睡眠干预措施后COVID-19护理.
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