希望:在患有癌症的患者中,对西增强型小组心理治疗进行试点研究
Benjamin R Lewis1, Eric L Garland2, Kevin Byrne1
1Huntsman Mental Health Institute (B.R.L., K.B., T.D.), University of Utah, Salt Lake City, Utah, USA.
Journal of pain and symptom management
|June 11, 2023
概括
以psilocybin辅助的群体治疗对患有抑郁症的癌症患者来说是有前途的. 这项试点研究发现它是安全有效的,在六个月内显著减少了症状.
科学领域:
- 精神病学是一个精神病学.
- 在瘤学瘤学.
- 心理药理学 心理药理学
背景情况:
- 松素辅助心理治疗显示出在严重医疗疾病中治疗抑郁症的潜力.
- 基于个人的psilocybin治疗提出了可扩展性和资源挑战.
- 群体治疗模式为更广泛的可访问性提供了一个潜在的解决方案.
研究的目的:
- 评估在患有抑郁症的癌症患者中使用psilocybin辅助小组治疗的安全性和可行性.
- 评估这种新型治疗方法的临床结果和疗效.
- 报告关于安全性和有效性的六个月后续数据.
主要方法:
- 一个开放的标签,试点可行性和安全性研究 (HOPE试验).
- 参与者在三个星期内接受了三次准备小组会议,一次高剂量psilocybin会议和三次整合会议.
- 结果措施是在基线,两周和干预后26周收集的.
主要成果:
- 十二名参与者完成了试验,没有严重的不良事件归因于psilocybin.
- 在临床上,抑郁症得分 (HAM-D) 的显著下降在两周 (21.5到10.09,P < 0.001) 和26周 (21.5到14.83,P = 0.006) 观察到.
- 大多数参与者实现了抑郁症状的缓解或临床显著改善.
结论:
- 对患有抑郁症的癌症患者而言,psilocybin辅助群体治疗是安全的和可行的.
- 组模型显示了潜在的有效性和治疗师时间的显著减少.
- 对这种群体治疗模式进行进一步的研究是有必要的,以获得更广泛的应用.
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