在阿根廷的一家普通医院中感染了与社区相关的Clostridioides difficile感染
Barbara Fox1, Valentina Ricci1, Silvina Bergese1
1Hospital Alemán, Buenos Aires, Argentina.
Anaerobe
|June 11, 2023
概括
越来越多的人认识到社区获得的困难菌感染 (CDI). 这项研究发现,社区CDI患者比医院相关病例年轻,并发病率较低,并不那么严重,抗生素使用是关键的风险因素.
科学领域:
- 传染性疾病 传染性疾病
- 流行病学 流行病学
- 微生物学 微生物学
背景情况:
- 困难菌感染 (CDI) 是传染性腹的一个重要原因.
- 虽然历史上被认为与医疗保健相关,但CDI现在在社区环境中得到了认可.
- 了解社区获得的CDI的流行病学对于公共卫生至关重要.
研究的目的:
- 调查CDI病例的流行病学起源.
- 将社区相关的CDI与医疗机构相关的CDI进行比较.
- 分析人口统计,并发病,风险因素,严重程度和死亡率差异.
主要方法:
- 单中心回顾性研究.
- 从2014年1月到2019年12月的CDI案件分析.
- 社区获得的CDI (34.4%的病例) 与医疗机构相关的CDI的比较.
主要成果:
- 社区CDI患者显著年轻 (53岁与65岁相比),并较少出现并发症 (查尔森指数1.65与3.98).
- 社区CDI病例通常不那么严重,仅报告了一例严重病例.
- 90天内使用抗生素是主要确定的风险因素 (65%),尽管7名患者没有明确的风险因素.
结论:
- 社区获得的CDI占案件的很大一部分.
- 与医疗保健相关的CDI相比,社区CDI表现出不同的流行病学和临床特征.
- 需要进一步的研究来了解没有确定的风险因素的患者的风险因素.
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