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对比儿科肝移植的结果

Kamil Yalçın Polat¹, Şerafettin Yazar¹, Serdar Aslan¹

¹Organ Transplantation Center, Bahçelievler Memorial Hospital, Istanbul, Turkey.

Transplantation proceedings

|June 11, 2023

概括

儿科肝移植显示出良好的生存率,特别是当胆道,血管和传染性并发症得到有效管理时. 对于患有末期肝衰竭的儿童来说,长期结果是有希望的.

科学领域:

儿科肝病学儿科肝病学
移植手术移植手术
临床结果研究研究

背景情况:

肝移植是儿科末期肝衰竭的一个关键干预措施.
这项研究回顾了11年的儿科肝移植结果.
分析了影响生存的预后因素.

研究的目的:

介绍2012年至2022年3月期间进行的儿科肝移植 (Pe-LT) 的结果.
识别和分析影响患者和移植存活的预后因素.
为了比较中央和国家Pe-LT利率.

主要方法:

对人口统计数据,病因,先前手术和并发症的回顾性分析.
对术后结果的评估,包括机械呼吸,ICU停留和并发症.
使用单变量和多变量分析评估移植和患者存活率.

主要成果:

进行了229次Pe-LT,占该中心所有肝脏移植的21.35%.
移植存活率从<30天的87%到>3年的78%不等.
患者的生存率在<30天后为91.5%,在>3年后降至81.5%.

结论:

生存率在1年和5年是可比的,这表明成功的长期结果.
有效管理胆道,血管和传染性并发症是延长生存的关键.
在代谢性疾病 (93.8%) 和急性肝衰竭 (100%) 中观察到高5年生存率.

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