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一个新的参数来评估胎儿的Sylvian裂通过腹腔两维超声波
Qing Zeng1, Huaxuan Wen1, Yimei Liao1
1Department of Ultrasound, Affiliated Shenzhen Maternity & Child Healthcare Hospital, Southern Medical University, Shenzhen, Guangdong, China.
Ultrasound in medicine & biology
|June 11, 2023
概括
在胎儿大脑成像中,可以使用超声波测量西尔维亚裂高原角 (SFPA). 低于0°的SFPA可能表明皮质发育形,有助于产前诊断.
科学领域:
- 神经成像是一种神经成像.
- 胎儿的发育 胎儿的发育
- 医学超声波 医学超声波
背景情况:
- 席尔维亚裂高原的倾斜是胎儿大脑发育的一个关键但未被定量化的方面.
- 对胎儿大脑解剖学的准确评估对于早期发现发育异常至关重要.
研究的目的:
- 介绍和评估西尔维亚裂高原角 (SFPA) 作为轴向胎儿大脑视图中的新型度量.
- 为了确定SFPA测量在怀孕23-28周之间的可靠性和诊断潜力.
主要方法:
- 对180例正常和3例异常单子妊娠 (妊娠23-28周) 的前性超声波评估.
- 在三个轴平面 (横静脉,横心脏,横大脑) 中测量SFPA,使用二维横腹部图像.
- 使用类内相关系数 (ICC) 评估观察者内部和观察者间的重复性.
主要成果:
- 正常病例显示SFPA>0°,而异常病例显示SFPA<0°.
- 对于SFPA测量,观测者内部和观测者间的重复性非常好 (ICC分别为0.971和0.936).
- 在跨大脑平面和跨脑膜/跨腹膜平面 (p <0.05) 之间,在SFPA中发现了显著的差异.
结论:
- 在怀孕23-28周之间的正常胎儿中,SFPA测量是稳定的和可靠的,0°作为潜在的切断点.
- SFPA <0°可能作为皮质发育形的宝贵产前标志物,特别是前骨-骨性形.
- 在临床SFPA评估西尔维亚裂时,建议使用跨体平面.
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