与疾病相关的营养不良,并有炎症和缓解症
Maurizio Muscaritoli1, Giovanni Imbimbo1, Harriët Jager-Wittenaar2
1Department of Translational and Precision Medicine, Sapienza University of Rome, Rome, Italy.
Clinical nutrition (Edinburgh, Scotland)
|June 11, 2023
概括
发症和与疾病相关的营养不良 (DRM) 与炎症密切相关. 未来的研究旨在开发一个风险预测分数,可测性/营养不良的表型,考虑到肌肉/脂肪代谢和营养摄入因素.
科学领域:
- 临床营养学 临床营养学
- 老年病的医生 老年病的医生
- 代谢过程中的代谢.
背景情况:
- 欧洲临床营养和新陈代谢学会 (ESPEN) 在2010年定义了长症,将其等同于与疾病相关的营养不良 (DRM) 和炎症.
- 最近的讨论 (2020-2022) 探讨了白血病和DRM之间的细微差别,炎症的作用和评估方法.
研究的目的:
- 分析长和与疾病相关的营养不良 (DRM) 与炎症之间的关系.
- 提出一个框架,为未来的预测得分可卡西克/营养不良的表型.
主要方法:
- 审查ESPEN特别利益小组 (SIG) 内的现有证据和专家讨论.
- 考虑全球营养不良领导倡议 (GLIM) 框架.
主要成果:
- 鉴定了缓冲症和DRM之间的相似之处和差异.
- 强调了DRM中炎症的重要性.
- 提出了预测风险评分的未来方向.
结论:
- 发症和伴有炎症的DRM是复杂的疾病,需要深入了解细微差别.
- 建议使用预测得分来量化导致卡赫克西亚和营养不良的因素.
- 已经确定了DRM和缓解症的新视角.
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