助孕生殖技术增加了孕前的风险
Molly S Kornfield1, Susan B Gurley2, Lisa A Vrooman3
1Division of Reproductive Endocrinology & Infertility, Department of Obstetrics & Gynecology, Oregon Health & Science University, Portland, OR, USA.
Current hypertension reports
|June 11, 2023
概括
辅助生殖技术 (ART) 与孕前的更高风险有关. 特定的ART程序和潜在的生物机制有助于增加怀孕的风险,需要进一步研究以获得更安全的结果.
科学领域:
- 生殖医学 生殖医学
- 产科和妇科 产科和妇科
背景情况:
- 辅助生殖技术 (ART) 涵盖了克服不孕症的各种程序.
- 孕前是一种严重的妊娠并发症,其特点是高血压.
研究的目的:
- 审查和综合当前关于ART和孕前风险之间的关联数据.
- 确定特定的ART程序和潜在的机制,有助于产前.
主要方法:
- 对现有的临床和临床前研究进行系统审查.
- 对回顾性临床数据和实验发现的分析.
主要成果:
- 大多数研究表明ART与妊娠前风险增加之间存在相关性.
- 在体外胚胎处理,激素刺激和性子捐赠是涉及的ART因素.
- 潜在的机制包括表观遗传变化,荷尔蒙因素和免疫反应.
结论:
- 与ART怀孕相关的是患孕前的风险增加.
- 建议在ART治疗计划中考虑降低孕前风险.
- 进一步的研究,包括临床和动物研究,对于理解和减轻这种风险至关重要.
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