[基本震动:我们只是在分裂毛发吗? 非运动症状和基本震-加上]
1Hospital de la Santa Creu i Sant Pau, 08025 Barcelona, España.
Revista de neurologia
|June 12, 2023
概括
在基本震 (ET) 中,越来越多地认识到非运动症状. 然而,ET-plus的概念需要更多的科学证据才能被广泛采用,因为诊断的复杂性.
科学领域:
- 神经学 神经学
- 运动障碍 运动障碍
背景情况:
- 非运动症状 (NMS) 在基本震 (ET) 中越来越多地被识别出来.
- 在ET中,原发性NMS与因残疾而产生的二次症状之间的区别尚不清楚.
- 目前对NMS的评估和治疗在ET护理中没有标准化.
研究的目的:
- 审查当前关于基本震非运动症状的证据.
- 评估有争议的"ET-plus"概念及其临床实用性.
主要方法:
- 对基本震中非运动症状研究的分析.
- 对支持或反驳"ET-plus"术语的文献进行审查.
主要成果:
- 与对照组相比,ET患者经常观察到非运动性症状.
- "ET-plus"这个术语是为了解决研究中的表型异质性而提出的.
- "ET-plus"的研究研究缺乏病理基础和重大缺陷.
结论:
- 在没有客观生物标志物的情况下,仅仅基于临床表现来区分ET和"ET-plus"是具有挑战性的.
- 建议谨慎使用新的术语,如"ET-plus"在没有强有力的科学验证的情况下.
- 需要进一步的研究来澄清ET非运动症状的性质,并验证新的分类.
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