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手术部位感染对健康实用值的影响:元分析
Agi M McFarland1, Sarkis Manoukian1,2, Helen Mason1,2
1Faculty of Health Sciences and Sport, University of Stirling, Stirling, UK.
The British journal of surgery
|June 12, 2023
概括
手术部位感染 (SSIs) 显著降低患者的生活质量. 这一元分析量化了SSI的效用损失,为预防策略和经济评估提供了必要的数据.
科学领域:
- 医疗保健经济学 医疗经济学
- 传染病流行病学 传染病流行病学
- 生活质量研究 研究 生命质量研究
背景情况:
- 手术部位感染 (SSIs) 是一个重大问题,对患者的生活质量产生负面影响.
- 现有的文献缺乏SSI实用值的元分析,这阻碍了准确的负担估计和预防投资决策.
研究的目的:
- 进行与手术部位感染 (SSI) 相关的实用值的首次元分析.
- 提供短期和长期SSI负担的综合估计.
- 为传染病预防规划和经济建模提供信息.
主要方法:
- 在PubMed,MEDLINE,CINAHL和NHS经济评估数据库的系统文献搜索 (2022年4月).
- 包括15项研究 (2817名患者),其中包括有SSI和没有SSI的成年人的生活质量数据.
- 使用随机效应模型进行元分析,将实用值转换为EuroQol 5D (EQ-5DTM) 估计值.
主要成果:
- 在六项研究中,EQ-5DTM实用性的聚合平均差异为-0.08 (95% CI-0.11至-0.05).
- 深度SSI与平均EQ-5DTM效用差异为-0.10 (95%CI-0.14至-0.06) 相关.
- 对实用价值的负面影响随着时间的推移而持续.
结论:
- 这项研究提供了第一次综合估计手术部位感染 (SSI) 对生活质量的负担.
- 对各种SSI的EQ-5DTM实用性估计对于有效的感染预防计划至关重要.
- 这些发现支持经济建模的必要性,以证明SSI预防投资的合理性.
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