为医疗保健提供者提供心血管药物遗传学入门教程
Akinyemi Oni-Orisan1, Sony Tuteja2, Glenda Hoffecker2
1Department of Clinical Pharmacy, University of California San Francisco, San Francisco, California, USA.
Clinical pharmacology and therapeutics
|June 12, 2023
概括
心血管药物遗传学改善了治疗心脏病的药物安全性和有效性. 加强医疗保健提供者的教育对于克服障碍和在临床实践中实施这些进步至关重要.
科学领域:
- 药理学 药理学是指药理学的学科.
- 遗传学 遗传学 是一个
- 心脏病学 心脏病学
背景情况:
- 心血管药物遗传学有可能通过个性化药物治疗来改善患者的治疗结果.
- 教育有限,指导方针不一致和误解阻碍了心血管药物遗传学的临床采用.
- 有大量的研究,但可访问性和清晰性仍然是医疗保健专业人员面临的挑战.
研究的目的:
- 为医疗保健提供者和学生提供关于心血管药物遗传学的入门教育.
- 弥合知识差距,促进心血管医学中药物遗传学测试的临床实施.
- 赋予临床医生所需的理解,以利用药物遗传学为更好的患者护理.
主要方法:
- 该教程分为六个关键步骤,用于全面的学习.
- 涵盖了基本的药物遗传学概念,心血管应用,指导组织和相关药物类别.
- 包括一个患者病例研究,并讨论该领域的新兴领域.
主要成果:
- 该教程旨在为广泛的受众揭开心血管药物遗传学的神秘性.
- 它解决了更新,一致和明确的临床建议的需求.
- 专注于基于证据的药物遗传策略的实际应用和理解.
结论:
- 改善教育对于心血管药物遗传学的有效临床使用至关重要.
- 这将增强对药物遗传学的理解和应用,以改善心血管疾病的结果.
- 最终的目标是减少与心血管疾病相关的发病率和死亡率.
相关概念视频
Cardiomyopathy V: Interprofessional Care
18
Managing cardiomyopathy involves addressing underlying or precipitating causes, treating heart failure with medications, and implementing dietary changes and a balanced exercise and rest regimen.Lifestyle ModificationsCardiomyopathy patients should adopt a low-sodium diet to reduce fluid retention and manage heart failure. A personalized exercise and rest plan helps maintain physical fitness without overstraining the heart. Avoiding alcohol and tobacco is essential to prevent further damage to...
18
Blood Studies for Cardiovascular System I: Cardiac Biomarkers
204
Cardiac biomarkers are enzymes, proteins, and hormones released into the blood when cardiac cells are injured. They are powerful tools for triaging.
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
The essential diagnostic tools for detecting myocardial necrosis and monitoring individuals suspected of having acute coronary syndrome (ACS) include:
Troponins
Troponins, particularly cardiac troponins I and T, are the most precise and sensitive markers of myocardial injury. They are detectable within 4-6 hours of myocardial injury and remain...
204
Assessment of the Cardiovascular System I: Subjective Data
375
A thorough health history and physical assessment are essential for identifying cardiovascular disease (CVD) symptoms and distinguishing them from other health issues.
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
Initial Enquiry
Ask the patient about their primary concern and thoroughly explore all reported symptoms.
Medical History
Investigate past illnesses affecting the cardiovascular system, such as angina, anemia, rheumatic fever, congenital heart disease, stroke, thrombophlebitis, dysrhythmias, varicosities
Inquire about symptoms...
375
Cardiovascular Drugs: Classification based on Therapeutic Indications
2.9K
Cardiovascular diseases, encompassing a range of conditions, can significantly affect the heart's operations and the overall circulatory system. These conditions impair the heart's ability to pump blood, leading to a deficit in oxygen supply to crucial organs. Anomalies in the heart's electrical system, known as arrhythmias, can cause heartbeats to accelerate or slow down. Usually, heart rates increase during physical activity and decrease while resting or sleeping. However,...
2.9K
Overview of the Cardiovascular System
4.8K
The cardiovascular system is a vital transportation system in the body. It comprises the heart and blood vessels and facilitates the exchange of gases, nutrients, and waste products.
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...
Heart
The heart is the central pump of the cardiovascular system that circulates blood throughout the body. It comprises two atria receiving the blood and two ventricles pumping blood out of the heart. Their rhythmic contractions, called heartbeats, ensure that blood flow remains continuous.
Blood Vessels
Blood...
4.8K
Hypertension I: Introduction
25
Hypertension is a widespread, long-term medical condition where blood pressure in the arteries remains elevated. It is characterized by systolic blood pressure readings of 130 mm Hg or above or diastolic blood pressure (DBP) readings of 80 mm Hg or higher. Unmanaged hypertension poses significant health risks, making the distinction between primary (or essential) hypertension and secondary hypertension crucial, as their management and implications vary.Primary HypertensionPrimary hypertension,...
25


