在患有大动脉吐症的患者中,透气管与外科大动脉置换相比:倾向匹配的分析
Chi Zhou1, Zongyi Xia1, Yanxu Song1
1Department of Cardiology, The Affiliated Hospital of Qingdao University, Qingdao, Shandong, 266003, China.
Heliyon
|June 12, 2023
概括
过导管大动脉置换 (TAVR) 显示出类似的医院死亡风险,以手术大动脉置换 (SAVR) 纯大动脉吐 (AR). TAVR减少了再入院,但增加了心脏起器植入的风险.
科学领域:
- 心脏病学 心脏病学
- 干预心脏病学 干预心脏病学
- 心脏外科手术 心脏外科手术
背景情况:
- 纯大动脉吐 (AR) 管理的比较跨导管大动脉置换 (TAVR) 和手术大动脉置换 (SAVR) 之间是有限的.
- 很少有研究比较了TAVR和SAVR的安全性和短期预后,特别是在纯AR患者中.
研究的目的:
- 分析和比较纯AR患者的TAVR与SAVR的住院和早期到临时结局.
- 评估TAVR和SAVR在一大批纯AR患者中的安全性和有效性.
主要方法:
- 从2016-2019年对国家再接收数据库 (NRD) 的回顾性分析.
- 包括被诊断为纯AR的患者,他们接受了SAVR或TAVR.
- 使用倾向分数匹配来最大限度地降低TAVR和SAVR组之间的差异,结果是1820对匹配对.
主要成果:
- TAVR显示,住院死亡风险较低.
- 与SAVR相比,TAVR与30天 (HR:0.73) 和6个月 (HR:0.81) 的所有原因再入院的发病率较低.
- 与SAVR相比,TAVR显示30天 (HR:3.54) 和6个月 (HR:4.12) 永久心脏起器植入的发生率更高.
结论:
- 在纯AR患者中,TAVR和SAVR表现出类似的医院死亡风险.
- 与SAVR相比,TAVR提供了较低的30天和6个月所有原因和心血管再入院率.
- 尽管永久心脏起器植入的风险更高,但TAVR是纯AR患者的安全替代方案.
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