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Updated: Jul 27, 2025

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双向双样本的门德尔随机化分析揭示了互白素-18水平对后神经疼痛风险的因果关系

Xiao Liang1, Yuchao Fan2

  • 1Department of Anesthesiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.

Frontiers in immunology
|June 12, 2023
PubMed
概括

升高的介素-18 (IL-18) 蛋白质水平可能会因果性地增加患发热后神经疼痛 (PHN) 的风险. 这一发现为PHN预防和治疗策略提供了新的途径.

关键词:
双向的门德尔式随机化全基因组关联研究研究.疹子 疹子介质蛋白-18的使用方法术后性神经疼痛 术后性神经痛

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相关概念视频

Single Nucleotide Polymorphisms-SNPs01:05

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A single nucleotide polymorphism or SNP is a single nucleotide variation at a specific genomic position in a large population. It is the most prevalent type of sequence variation found in the human genome. Point mutations that occur in more than 1% of the population qualify as SNPs. These are present once every 1000 nucleotides on an average in the human genome. Replacement of a purine with another purine (A/G) or a pyrimidine with another pyrimidine (C/T) is known as a transition. In contrast,...
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