相关实验视频

Updated: Jul 27, 2025

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants

Long-term Behavioral and Reproductive Consequences of Embryonic Exposure to Low-dose Toxicants

Published on: March 6, 2018

在挪威学龄前儿童的产前有机酸暴露和执行功能

Amber M Hall¹, Alexander P Keil¹, Giehae Choi²

¹Department of Epidemiology, Gillings School of Public Health, University of North Carolina at Chapel Hill, Chapel Hill, North Carolina.

Environmental epidemiology (Philadelphia, Pa.)

|June 12, 2023

概括

产前暴露于有机酸 (OPEs) 可能会对学龄前儿童的执行功能 (EF) 产生负面影响. 关联因化学物质和儿童的性别而异,这表明潜在的性别特异性易受OPE的侵害.

科学领域:

环境健康环境健康
神经发育毒理学神经发育毒理学
儿科健康儿科健康

背景情况:

有机酸 (OPEs) 被广泛用作阻燃剂和增塑剂.
增加了OPE的使用,作为受监管化学品的替代品.
了解OPE对儿童发展的影响至关重要.

研究的目的:

调查产前有机酸 (OPE) 暴露与学龄前儿童执行功能 (EF) 之间的关联.
探索这些关联中的潜在的性别特异差异.

主要方法:

研究包括来自挪威母亲,父亲和儿童队列研究的340名学龄前儿童.
母亲的尿样测量了四种OPE代谢物:DPhP,DnBP,BBOEP和BDCIPP.
使用BRIEF-P和斯坦福-Binet第五版 (SB-5) 评估的执行功能.

主要成果:

在多个领域中,较高的丁酸 (DnBP) 与较差的EF有关.
基酸盐 (DPhP) 和1,3-二chloro-2-propyl) 酸盐 (BDCIPP) 与较低的语言工作记忆相关.
双基酸 (BBOEP) 与较低的教师评级抑制有关;DPhP显示对男孩的EF有性别特异性影响.

结论:

产前OPE暴露可能与学龄前儿童的执行功能受损有关.
根据孩子的性别观察到的关联变化表明对OPE的敏感性差异.
需要进一步的研究来证实这些发现并阐明机制.

关键词:

BBOEPEP BBOEPEP 这是一个很好的方法.BDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPPBDCIPP 行为行为行为.控制控制控制控制控制在 DPhP 的情况下,DPhP 是 DPhP.DnBP DnBP DnBP DnBP DnBP DnBP DnBP DnBP DnBP DnBP DnBP DnBP DnBP DnBP DnBP DnBP DnBP DnBP 情感上的情感感性的情感.执行职能执行职能执行职能阻燃剂是一种阻燃剂.抑制抑制的抑制作用这是一个MBRN.摩巴巴是什么意思摩巴巴是什么意思神经发育神经发育挪威挪威挪威挪威挪威有机酸盐 Ester 是一种有机酸盐.幼儿园学前教育幼儿园学前教育工作记忆工作记忆

更多相关视频

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Assessment and Evaluation of the High Risk Neonate: The NICU Network Neurobehavioral Scale

Published on: August 25, 2014

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Preclinical Model of Prenatal Delta-9-Tetrahydrocannabinol Exposure to Assess Its Impact on Neurodevelopmental Outcomes

Published on: February 28, 2025

相关概念视频

Attention-Deficit/Hyperactivity Disorder

Attention-Deficit/Hyperactivity Disorder

Attention-deficit/hyperactivity disorder (ADHD) is a neurodevelopmental disorder characterized by persistent inattention, hyperactivity, and impulsivity. It affects approximately 5-8% of children globally, with around 60-70% of cases persisting into adulthood. ADHD has significant implications for educational attainment, social interactions, and occupational success.
Diagnostic Criteria and Symptoms
To diagnose ADHD, symptoms must manifest before age 12 and be evident across multiple settings....

Information Processing Approach

Information Processing Approach

The information-processing theory of cognitive development centers on fundamental mental processes, including attention, memory, and problem-solving skills. Researchers in this field examine how cognitive abilities, such as working memory, evolve and influence children's overall development. Studies indicate that children with stronger working memory tend to excel in reading comprehension, math, and problem-solving compared to peers with less efficient memory skills. Low working memory is...