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Updated: Jul 27, 2025

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在减弱V30M TTR诱导的家族性粉样性多神经病变时,以防御素为基础的治疗性的设计

G Chandrasekhar1, H Pengyong2, G Pravallika1

  • 1Quantitative Biology Lab, Department of Integrative Biology, School of Bio Sciences and Technology, Vellore Institute of Technology (VIT, Deemed to Be University), Vellore, Tamil Nadu 632014 India.

3 Biotech
|June 12, 2023
PubMed
概括

一种新型的治疗性,CKTE,来自Nicotiana alata Defensin 1,在防止V30M突变型transthyretin (TTR) 蛋白质的错误折叠和聚合方面显示出希望,这是家族性粉样性多神经病的关键因素.

关键词:
离散的分子动力学.家庭性粉样性多神经病变.正常模式分析正常模式分析基于的治疗药物.蛋白质聚合蛋白质的聚合.

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