在COVID后疲劳中神经调节失调
Anne M E Baker1, Natalie J Maffitt1, Alessandro Del Vecchio2
1Faculty of Medical Sciences, Newcastle University, Newcastle Upon Tyne, NE2 4HH, UK.
Brain communications
|June 12, 2023
概括
长期COVID疲劳可能源于神经和肌肉问题. 研究发现,在COVID后疲劳的患者中,大脑电路不活跃,自主功能障碍和骨肌肉变化.
科学领域:
- 神经科学是一个神经科学.
- 免疫学 免疫学 免疫学
- 病理学 病理学 病理学
背景情况:
- 长期COVID,SARS-CoV-2感染后的疾病,经常包括衰弱的疲劳.
- 导致COVID后疲劳的潜在神经机制尚不清楚.
研究的目的:
- 为了调查神经,外围和自主神经系统的疲劳的基础在轻度COVID-19感染后的个人.
主要方法:
- 招募了37名自报COVID-19后疲劳的志愿者.
- 进行了全面的行为和神经生理评估.
- 结果与52个年龄和性别匹配的健康对照进行了比较.
主要成果:
- 在COVID后疲劳的个体中,特定皮质电路的低活性被确定.
- 观察到自主功能的失调.
- 在骨肌肉组织中检测到肌病变化.
结论:
- 后COVID疲劳似乎是一个单独的实体,具有个别的变化,而不是不同的综合征.
- 研究结果表明,有潜在的客观标志物用于监测疾病和制定干预措施.
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