不是所有的都是甜的 - - 儿科膜瘤
George V Koshy1, Michael H Fitzpatrick1, Chadd K Kraus1
1Department of Emergency Medicine Geisinger Health Danville Pennsylvania USA.
概括
脑膜瘤是儿童中罕见的中枢神经系统瘤,现在根据位置,组织学和遗传学进行分类. 治疗包括手术切除,然后进行放射治疗.
科学领域:
- 神经瘤学神经瘤学
- 儿科瘤学 儿科瘤学
- 中枢神经系统瘤 中枢神经系统瘤
背景情况:
- 膜瘤是一种罕见的恶性瘤,起源于放射性质细胞.
- 它们是儿童中第三个最常见的中枢神经系统瘤,主要位于后腔.
研究的目的:
- 为了概述当前对表层瘤的理解.
- 为了突出表达正在发展的表瘤分类系统.
- 概述表瘤的标准治疗方法.
主要方法:
- 综述最近关于表瘤分类和治疗的文献.
- 对更新的基因病理学和遗传学子组的分析.
- 目前标准护理协议的总结.
主要成果:
- 经过修订的分类现在根据解剖位置,组织病理特征和遗传子组对表瘤进行分类.
- 这些子组表现出不同的临床表现和疾病进展模式.
- 已建立的治疗方案仍然是最大的手术切除,然后是辅助放射治疗.
结论:
- 精确地分类表瘤对于预测患者的结果至关重要.
- 个性化治疗策略可能会从进一步了解分子和遗传子组中出现.
- 最大安全的手术切除和放射治疗仍然是尾瘤管理的基石.
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