与非癌症患者相比,治疗前癌症的基线心电图异常:倾向性得分分析
Lolita Golemi1, Akash Sharma2, Alexandra Sarau3
1Department of Internal Medicine, Saint Louis University School of Medicine, St. Louis, MO, USA.
Cardiology research
|June 12, 2023
概括
癌症患者比非癌症患者显示出更多的治疗前心电图 (ECG) 异常,这表明基线心血管风险更高. 建议在治疗前对所有癌症患者进行心电图,以评估这种风险.
科学领域:
- 心脏病学 心脏病学
- 在瘤学瘤学.
- 医学诊断 医学诊断 医学诊断
背景情况:
- 之前的研究集中在癌症患者治疗后的心电图异常.
- 在癌症患者中评估基线心血管 (CV) 风险需要在治疗前进行评估.
- 将癌症患者与非癌症人群进行比较,为基线心血管风险提供了关键的见解.
研究的目的:
- 为了比较癌症患者的治疗前心电图 (ECG) 异常与非癌症手术患者群体.
- 在开始治疗之前,评估癌症患者的基线心血管风险.
- 为了识别癌症患者在诊断时普遍存在的特定心电图异常.
主要方法:
- 一项综合前性和后性队列研究包括癌症患者和年龄/性别匹配的非癌症对照.
- 分析了电脑化的心电图解释,其中的一个子组接受了盲目的心脏病学家审查.
- 使用倾向性得分匹配和随机表分析与概率比率Chi-square统计数据.
主要成果:
- 与非癌症对照组相比,治疗前的癌症患者表现出异常心电图的可能性更高 (OR:1.55;95% CI:1.05-2.30).
- 在黑人患者中,心电图异常更为普遍 (P=0.001).
- 与普通人群相比,癌症患者的QT延长和心室内导电缺陷较少,但心律失常和心房动 (AF) 较多.
结论:
- 治疗前的心电图显示,癌症患者的异常患病率较高,这意味着基线CV风险较高.
- 电心电图 (ECG) 是一种有价值,低成本的工具,用于癌症患者的治疗前心血管风险评估.
- 在癌症治疗前对所有癌症患者推进行例行心电图查.
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