非侵入性中央大动脉压力测量:在临床实践中的应用有什么限制?
Alejandro Diaz1, Yanina Zócalo2, Federico Salazar3
1Instituto de Investigación en Ciencias de la Salud, UNICEN-CCT CONICET, Tandil, Argentina.
Frontiers in cardiovascular medicine
|June 12, 2023
概括
准确的非侵入性中央大动脉血压 (aoBP) 测量需要方法上的共识. 记录,建模和校准的标准化对于可靠的临床和研究应用至关重要.
科学领域:
- 心血管生理学心血管生理学
- 生物医学工程 生物医学工程
- 临床研究方法论 临床研究方法论
背景情况:
- 中央大动脉血压 (aoBP) 评估在临床和研究环境中非常有价值.
- 非侵入性aoBP测量缺乏标准化的方法,阻碍了其广泛采用和跨研究的比较.
- 现有的aoBP估计方法在记录技术,数学模型和校准程序方面各不相同.
研究的目的:
- 突出在非侵入性aoBP评估中对方法透明度和共识的关键需求.
- 确定影响aoBP测量准确性和可重复性的关键因素.
- 讨论导致对aoBP量化缺乏共识的决定因素.
主要方法:
- 文献审查和对现有非侵入性aoBP测量方法的分析.
- 确定和讨论aoBP估计中的关键参数,包括记录地点,数学建模和脉冲波形校准.
- 考察导致该领域变化和缺乏共识的因素.
主要成果:
- 记录,数学建模和校准的方法变化对aoBP估计有很大的影响.
- 缺乏标准化阻碍了不同研究,种群和测量方法之间的数据比较.
- 缺乏共识的关键决定因素包括不同的校准方法和记录技术.
结论:
- 建立对非侵入性aoBP测量标准化方法的共识,对于提高其有效性和临床效用至关重要.
- 需要进一步的研究来澄清aoBP与外周血压的增量预测值.
- 标准化将有助于将aoBP纳入常规临床实践,并推进生理学研究.
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