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益生菌可以帮助解决儿童肥胖流行病吗?
Yaqin Wang1,2, Anne Salonen3, Ching Jian2,3
1School of Life and Health Technology, Dongguan University of Technology, Dongguan, China.
Frontiers in endocrinology
|June 12, 2023
概括
用益生菌向肠道微生物群显示出治疗儿童肥胖的前景. 需要更多的研究来了解益生菌如何影响儿科新陈代谢,以便有效的体重管理干预措施.
科学领域:
- 微生物学 微生物学
- 儿科内分泌学 儿科内分泌学
- 营养科学 营养科学
背景情况:
- 儿童肥胖是一个全球公共卫生危机,几乎没有有效的治疗方法.
- 肠道微生物失调症越来越多地与肥胖症的发展有关.
- 益生菌在临床前模型和成年人中显示出通过恢复肠道共生来减少脂肪的潜力.
研究的目的:
- 审查儿童肥胖症中的肠道微生物群特征.
- 为了探索代谢效益的前生物机制.
- 总结关于用于儿科体重管理的益生菌的临床试验.
主要方法:
- 在儿童肥胖中对常见肠道微生物群概况的文献综述.
- 对影响宿主新陈代谢的益生菌机制的概述.
- 综合从临床试验调查超重/肥胖儿童的益生菌干预措施的研究结果.
主要成果:
- 肠道微生物群的改变在儿科肥胖症中很常见.
- 益生菌可能通过调节肠道细菌来提供代谢益处.
- 在儿科体重管理中益生菌疗效的临床证据正在出现,但有限.
结论:
- 益生菌代表了儿童肥胖的潜在治疗途径.
- 需要进一步的研究来澄清益生菌作用的微生物群依赖机制.
- 了解这些机制对于开发针对儿童肥胖的有针对性的干预措施至关重要.
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