一种基于放射学肌肉间脂肪分析的诺米克图,用于在新诊断为2型糖尿病的患者中表明动脉硬化
Cong He1, Dong Xie1, Lin-Feng Fu1
1Department of Radiology, Shaoxing Second Hospital, Shaoxing, Zhejiang, China.
Frontiers in endocrinology
|June 12, 2023
概括
肌肉间脂肪组织 (IMAT) 的放射性分析可以在新型2型糖尿病 (T2D) 患者中确定动脉样硬化. 这种新型标志物通过更有效地评估心血管风险,有助于早期预防策略.
科学领域:
- 心血管成像 - 心血管成像
- 代谢障碍 代谢障碍 代谢障碍
- 放射学 放射学是一门学科.
背景情况:
- 在新诊断的2型糖尿病 (T2D) 患者中,早期发现动脉样硬化对于有效预防至关重要.
- 动脉样硬化对T2D患者构成重大风险,需要先进的诊断标志物.
研究的目的:
- 调查放射性肌肉间脂肪组织 (IMAT) 分析作为新诊断T2D患者动脉样硬化的新标记物的实用性.
- 为了比较临床模型,放射学模型和联合临床放射学模型在指示动脉样硬化及其严重性的有效性.
主要方法:
- 分析了549名新诊断T2D患者的队列.
- Carotid 斑块负担被用来评估动脉样硬化.
- 通过AUC和DeLong测试开发和评估了三种模型 (临床模型,基于胸部CT的IMAT的放射学模型和组合模型).
主要成果:
- 与临床模型相比,临床-放射学组合模型在指示动脉样硬化方面表现优越 (训练组中的AUC为0.934对比0.687).
- 组合模型在指示动脉样硬化严重程度方面也显示出更高的疗效 (AUC为0.824对比0.755用于临床和0.734用于训练集中的放射学).
- 放射性IMAT分析,特别是在组合模型中,在评估动脉样硬化风险和严重程度方面被证明是有效的.
结论:
- 放射性IMAT分析是新诊断T2D患者动脉硬化的一种新且有效的标志物.
- 开发的诺姆图为临床医生提供了一种定量工具,以评估动脉样硬化风险,整合放射性和临床数据以改善患者管理.
更多相关视频
09:21Human Brown Adipose Tissue Depots Automatically Segmented by Positron Emission Tomography/Computed Tomography and Registered Magnetic Resonance Images
Published on: February 18, 2015
12.2K
13:09Segmentation and Measurement of Fat Volumes in Murine Obesity Models Using X-ray Computed Tomography
Published on: April 4, 2012
16.2K
相关概念视频
01:21Imaging Studies for Cardiovascular System IV: CMRI
65
Cardiovascular magnetic resonance imaging, or CMRI, is a non-invasive diagnostic test that employs a magnetic field and radiofrequency waves to create precise images of the heart and arteries. It provides comprehensive information about cardiac anatomy, function, perfusion, and tissue characterization without ionizing radiation.IndicationsCMRI diagnoses various heart conditions, including tissue damage from heart attacks, ischemic heart disease, myocarditis, aortic issues (tears, aneurysms,...
65
01:20Imaging Studies for Cardiovascular System III: X-Ray
219
The most common cardiovascular diagnostic test is an X-ray. It produces images of the heart, blood vessels, and adjacent structures.
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
Definition and Purpose
An X-ray, or radiograph, is a non-invasive method that uses ionizing radiation to take images of internal structures. It is mainly used in cardiac imaging to examine the heart, lungs, and major blood vessels, aiming to identify abnormalities in the heart's size, shape, and position, such as heart failure, congenital defects, and vascular...
219
01:25Imaging Studies for Cardiovascular System VI: Calcium -Scoring CT
42
Calcium-Scoring CT ScanA calcium-scoring CT scan, also known as coronary artery calcium (CAC) scan, detects calcium deposits in the coronary arteries. This test assesses the risk of coronary artery disease (CAD), which can lead to cardiovascular events such as angina, heart failure, and sudden cardiac arrest.A calcium-scoring CT scan is generally recommended for individuals at intermediate risk of CAD without symptoms. It includes:Men aged 40-75 and women aged 50-75: Especially those with a...
42