用新型大麻提取物再生头发:一个案例系列
1Nex Therapeutics, St. Pete Beach, Florida 33706, USA.
International journal of trichology
|June 12, 2023
概括
含有CBD,THCV和CBDV的局部大麻提取物显著改善了androgenetic脱发症患者的头发再生. 这种新的治疗方法在与现有疗法相比显示出更优异的结果,并且没有出现任何不良影响.
科学领域:
- 内分泌学 在内分泌学.
- 皮肤病学 皮肤病学
- 植物化学 植物化学
背景情况:
- 内分泌大麻素系统 (ECS) 通过调节炎症和再生过程来调节平衡.
- 植物性大麻素如大麻 (CBD),四大麻 (THCV) 和大麻 (CBDV) 与ECS相互作用.
- 这些大麻素通过涉及CB1,TRPV1和TRPV4受体的新机制,显示出治疗头发再生的潜力.
研究的目的:
- 评估一种富含CBD,THCV和CBDV的局部大麻提取物在患有雄激素脱发症 (AGA) 的受试者头发再生的疗效.
- 为了将这种大麻提取物配方的效果与以前的研究和现有的脱发治疗方法进行比较.
主要方法:
- 一个案例系列研究涉及31名患有AGA的受试者,他们在六个月内每天一次使用局部大麻提取物配方.
- 在治疗前和治疗后进行了头发计数,永久纹身标记了最大脱发区域.
- 参与者提供了对头皮覆盖面的定性反,独立的医生对标准化照片的审查评估了改善.
主要成果:
- 所有受试者都经历了头发的再生,男性的平均增长率为246%,女性为127%.
- 观察到头皮覆盖面的显著改善,从轻微到广泛.
- 没有报告任何不良影响,受试者对感知到的改善表示高度满意.
结论:
- 含有CBD,THCV和CBDV的局部大麻提取物配方在促进AGA的头发再生方面表现出显著的有效性.
- 这些大麻素可能会作为CB1抗剂和TRPV1激动剂,具有薄荷醇的潜在协同效应.
- 这种新的治疗方法提供了一个潜在的优越和补充选择,以现有的疗法,如费纳斯特和米诺克西迪尔.
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