慢性病毒性肝炎中的肉类:从概念到临床相关性
Marta Paula Pereira Coelho1, Pedro Alves Soares Vaz de Castro2, Thaís Pontello de Vries1
1Sciences Applied to Adult Health Care Post-Graduate Programme, Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte 30130-100, Minas Gerais, Brazil.
World journal of hepatology
|June 12, 2023
概括
慢性病毒性肝炎,包括乙型肝炎 (CHB) 和型肝炎 (CHC),与肌肉质量丧失的萨尔科佩尼亚有关. 了解这种联系对于综合患者护理至关重要.
科学领域:
- 肝病学 肝病学是一种肝病学.
- 病毒学 病毒学
- 老年病的医生 老年病的医生
背景情况:
- 慢性乙型肝炎 (CHB) 和慢性乙型肝炎 (CHC) 是肝硬化和肝细胞癌 (HCC) 的主要原因.
- 乙型肝炎病毒 (HBV) 和乙型肝炎病毒 (HCV) 感染导致肝外表现,现在包括肉症.
- 肌肉质量或功能丧失的萨尔科佩尼亚影响了23.0%-60.0%的晚期肝病患者.
研究的目的:
- 审查慢性病毒性肝炎中萨尔科佩尼亚的概念,患病率,临床相关性和机制.
- 强调与HBV和HCV患者骨肌肉损失相关的临床结果.
- 突出需要一种综合方法来管理CHB和CHC的肉症.
主要方法:
- 关于慢性病毒性肝炎中萨尔科佩尼亚研究的文献综述.
- 流行率,临床相关性和潜在机制的分析.
- 重点是临床结果和病毒-宿主-环境相互作用.
主要成果:
- 萨科佩尼亚是慢性病毒性肝炎的一个重要问题,独立于肝病阶段.
- 在研究病因和石症测量方法中存在异质性.
- 萨科佩尼亚和CHB/CHC之间的相互作用需要在现实环境中进一步澄清.
结论:
- 麻症是慢性HBV和HCV感染中复杂的多因素状况.
- 综合医疗,营养和体育教育对于管理CHB和CHC患者的萨科佩尼亚至关重要.
- 需要进一步的研究,以充分阐明病毒-宿主-环境在萨尔科佩尼亚发展中的相互作用.
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