冠状病毒病2019年和儿童的胃肠道疾病
Anna Röckert Tjernberg1, Petter Malmborg2,3,4, Karl Mårild5,6
1Department of Pediatrics, Kalmar County Hospital, Region Kalmar County, Kalmar S-391 85, Sweden.
Therapeutic advances in gastroenterology
|June 12, 2023
概括
患有胃肠道 (GI) 疾病的儿童,包括乳病 (CeD) 和炎症性肠病 (IBD),不会面临严重COVID-19的更高风险. 目前的证据没有将COVID-19与这些儿科胃肠道疾病的发展联系起来.
科学领域:
- 儿科胃肠病学 儿科胃肠病学
- 传染性疾病 传染性疾病
- 免疫学 免疫学 免疫学
背景情况:
- COVID-19大流行影响了全球健康,不同年龄段的疾病严重程度各不相同.
- 儿童通常比成年人体验较轻微的COVID-19,但可能呈现出更明显的胃肠道 (GI) 症状.
- 儿童发育中的免疫系统可能与成人不同地影响COVID-19对疾病发展的影响.
研究的目的:
- 审查COVID-19和儿科胃肠道疾病之间的潜在双向关系.
- 专注于常见的疾病:功能性肠道疾病 (FGID),腹腔疾病 (CeD) 和炎症性肠道疾病 (IBD).
主要方法:
- 对调查COVID-19和儿科胃肠道疾病的研究进行文献综述.
- 对有关疾病表现,严重程度和潜在触发因素的现有数据的分析.
主要成果:
- 患有胃肠道疾病的儿童,特别是CeD和IBD,似乎没有增加COVID-19严重结果 (住院,重症监护,死亡) 的风险.
- 没有足够的证据证明COVID-19是儿童FGID,CeD或IBD的直接原因或触发因素.
- 感染是已知的CeD和IBD病原发生的潜在环境因素,也是FGID的触发因素.
结论:
- 目前的数据表明,儿科胃肠道患者的严重COVID-19风险并不高.
- 需要进一步的研究来探索COVID-19和儿科胃肠道疾病之间的潜在长期影响和因果关系,因为数据稀缺和潜在的延迟期.
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