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Updated: Jul 26, 2025

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
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选新型非编码变异的挑战,这些变异有助于遗传复杂的表型

Christopher P Castro1, Adam G Diehl1, Alan P Boyle2,1

  • 1Department of Computational Medicine and Bioinformatics, University of Michigan, Ann Arbor, MI 48109, USA.

HGG advances
|June 12, 2023
PubMed
概括

鉴定自闭症谱系障碍 (ASD) 的遗传原因是具有挑战性的. 研究显示,注释质量和变异可靠性,而不仅仅是样本大小,阻碍了与新变异的关联.

关键词:
自闭症遗传学 自闭症遗传学这是一种de novo突变.非编码的变化变化.

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