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癌症的"甜蜜"路径:专注于细胞葡萄糖代谢

Carla Iacobini1, Martina Vitale1, Giuseppe Pugliese1

  • 1Department of Clinical and Molecular Medicine, "La Sapienza" University, Rome, Italy.

Frontiers in oncology
|June 12, 2023
PubMed
概括

癌细胞通过缺氧诱导因子-1α (HIF-1α) 和酸盐激酶M2 (PKM2) 重新连接能量代谢,从而驱动华堡效应. 这种代谢转变也在糖尿病中可见,这表明癌症和心脏代谢疾病之间存在联系.

关键词:
华堡效应是什么? 华堡效应有氧糖解有氧糖解.在糖尿病中,糖尿病是血糖性糖尿病.缺氧诱导因子 (HIF) - 1αα.这是一种炎症炎症炎症炎症.甲基氧素 (MGO) 是一种氧化式的光化.酸激酶M异形2的2个形式

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