一个罕见的腹痛原因:埃尔德海姆-切斯特病
Arjun Chatterjee1, Jaime de la Fuente2, Karen L Rech3
1Department of Internal Medicine, Cleveland Clinic, Cleveland, OH.
ACG case reports journal
|June 12, 2023
概括
埃尔德海姆-切斯特病是一种罕见的质细胞瘤,可以出现不寻常的胃肠道症状. 诊断包括识别特定的囊细胞标记物和BRAF V600E突变.
科学领域:
- 在瘤学瘤学.
- 病理学 病理学 病理学
- 胃肠病学 胃肠病学
背景情况:
- 埃尔德海姆 - 切斯特病 (ECD) 是一种罕见的非朗格汉斯细胞囊炎.
- 电脑心脏病通常影响成年人,并可能涉及多个器官.
- 胃肠道ECD的表现不常见.
研究的目的:
- 报告一个罕见的埃尔德海姆-切斯特病病例.
- 为了突出ECD的异常胃肠道和背部表现.
- 为了强调囊细胞标记物和BRAF V600E突变的诊断重要性.
主要方法:
- 一个65岁的男性有相关症状的病例报告.
- 计算机断层扫描血管图与肠道图像成像.
- 腹腔镜活检用于组织病理学检查.
- 针对CD163,XIIIa因子和BRAF V600E的免疫组织化学染色.
主要成果:
- 患者呈现出出血,夜间出汗,恶心,腹和腹痛.
- 图像检查显示,脏和尿道被包围的膜纤维化.
- 活检显示纤维质组织与质细胞透物,淋巴细胞和血细胞.
- 组织细胞表达了CD163,XIIIa因子和BRAF V600E突变.
结论:
- 病人被诊断出患有埃德海姆-切斯特病.
- 这个案例强调了ECD的多样化和不常见的表现.
- 准确的诊断依赖于整合临床,成像和病理发现,包括分子标记物.
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