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Updated: Jul 26, 2025

Sequential Salt Extractions for the Analysis of Bulk Chromatin Binding Properties of Chromatin Modifying Complexes
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Published on: October 2, 2017

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本质上 BRCA1/BARD1 乱的区域有助于染色质的招募和无处不在

Samuel R Witus1, Lisa M Tuttle1, Wenjing Li2

  • 1Department of Biochemistry, University of Washington, Seattle, WA, USA.

The EMBO journal
|June 12, 2023
PubMed
概括

作为一种瘤抑制剂的BRCA1/BARD1利用本质上有障碍的区域来结合DNA和核细胞,从而增强DNA损伤的修复能力. 这种相互作用对于将BRCA1/BARD1招募到染色质和支持细胞存活至关重要.

关键词:
这就是BRCA1/BARD1的原因.修复DNA的修复DNA的修复在这种情况下,染色染色素本质上是无序的区域.在任何地方都是无处不在的.

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