红细胞分布宽度与血小板比率在新生婴儿小羊中具有败血症
Rebeca Scalco1, Gabriela Novo de Oliveira1, Bruna da Rosa Curcio2
1Department of Medicine and Epidemiology, School of Veterinary Medicine, University of California, Davis, California, USA.
Journal of veterinary internal medicine
|June 12, 2023
概括
红细胞分布宽度与血小板比率 (RPR) 可以帮助诊断小的败血症. 较高的RPR值表明感染败血症的可能性更高,并可以预测小的结果.
科学领域:
- 兽医医学 兽医医学 兽医医学
- 新生儿护理 新生儿护理
- 诊断标记物 诊断标记物
背景情况:
- 新生儿小的败血症诊断需要快速准确的标记物.
- 红细胞分布宽度 (RDW) 与血小板比率 (RPR) 是人类败血症中观察到的潜在炎症标志物.
研究的目的:
- 为了研究RPR和新生儿小的败血症之间的相关性.
- 在这个人群中评估RPR对败血症的预测和预后价值.
主要方法:
- 一项追溯病例控制研究,涉及317只住院的新生小 (≤7天大).
- 从全血细胞计 (CBC) 数据计算RPR.
- 使用统计测试,比较了败血症,非败血症和健康小之间的RPR.
- 多变量后勤回归和生存分析 (Kaplan-Meier) 用于评估预测和预后能力.
主要成果:
- 败血症小与非败血症和健康小相比,呈现出明显更高的RPR值 (P < .0001).
- RPR在预测败血症方面表现出高准确度 (AUC = 82.1%),最佳截止值为0.09.
- 生存分析表明基于RPR水平的预后值.
结论:
- RPR是一种实用,廉价和易于计算的标记,来自CBC数据.
- RPR,与CBC结合,可以帮助诊断新生儿小的败血症.
- RPR有助于估计败血症新生儿小羊的预后.
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