肺功能变化与患者报告的肺癌手术结果之间的关系
Hideo Ichimura1,2, Keisuke Kobayashi3, Masahiko Gosho4
1Department of Thoracic Surgery, Hitachi General Hospital, Hitachi, Ibaraki, 317-0077, Japan. ichimura@md.tsukuba.ac.jp.
Surgery today
|June 12, 2023
概括
肺癌手术后肺功能 (PF) 的变化与患者报告的结果 (PRO) 之间存在微弱的相关性. 需要进一步的研究来增强术后患者的体验和恢复.
科学领域:
- 胸部外科手术 胸部外科手术
- 肺部医学 肺部医学
- 在瘤学瘤学.
- 患者报告的研究结果研究结果
背景情况:
- 肺癌手术显著影响患者的生活质量.
- 了解生理恢复和患者体验之间的联系对于改善术后护理至关重要.
研究的目的:
- 为了研究肺功能 (PF) 变化和肺癌手术后患者报告的结果 (PROs) 之间的关系.
- 评估不同的外科手术方法如何影响PF和PRO.
主要方法:
- 262名为癌症进行肺切除的患者在手术前和手术后一年完成了生活质量调查问卷 (EORTC QLQ-C30,LC13).
- 在两个时间点进行了肺功能测试和PRO评估.
- 分析了两个队列:正在进行的协议队列和临床I期肺癌叶切除术合格队列.
主要成果:
- PF的变化与PRO的相关性很弱,包括全球健康状况,身体/角色功能,疲劳,疼痛,恶心,吐和财务困难 (相关系数0.1490.311).
- 情绪和社会功能的改善独立于PF变化.
- 亚叶切除可以比分叶切除更好地保存PF,切除可以特别减轻呼吸不良.
结论:
- 肺功能和肺癌手术后患者报告的结果之间的相关性很弱.
- 需要进一步的研究,以确定改善术后患者体验和康复的策略.
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