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在MSC中,葡萄糖皮质醇诱导的NOX/ROS/NF-κB信号的激活有助于GONFHH的发展

Huihui Xu1,2,3, Qinghe Zeng1,2,3, Kaiao Zou1,2,3

  • 1The First Affiliated Hospital of Zhejiang Chinese Medical University (Zhejiang Provincial Hospital of Chinese Medicine), Hangzhou, Zhejiang, 310006, China.

Apoptosis : an international journal on programmed cell death
|June 12, 2023
PubMed
概括

葡萄糖皮质类药物 (GCs) 通过促进介质干细胞 (MSCs) 中的氧化应激来诱导股骨头骨 necrosis. 这一途径涉及NOX/ROS/NF-κB,导致细胞死亡和分化失衡,从而导致GONFH的发病.

关键词:
细胞灭亡 (apoptosis) 是一种死亡的过程.不同化的差异化这就是GONFH.介质细胞干细胞介质细胞干细胞.氧化应激是一种氧化应激.

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