[在患有严重神经疾病的患者中,四肢输液指数和乳酸之间的相关性]
Wen Guo1, Long Ma1, Tuerxun Tuerhong1
1Department of Intensive Care Unit, the First Affiliated Hospital of Xinjiang Medical University, Urumqi 830000, Xinjiang Uygur Autonomous Region, China.
Zhonghua wei zhong bing ji jiu yi xue
|June 12, 2023
概括
神经病患者的输液指数 (PI) 与血液中的乳酸有负相关性,表明PI.
科学领域:
- 神经学 神经学
- 临界护理医学 临界护理医学
- 生物医学工程 生物医学工程
背景情况:
- 神经病可以影响微循环.
- 评估微循环 perfusion 在神经病患者中至关重要.
- 输血指数 (PI) 是对外周循环的非侵入性测量.
研究的目的:
- 在神经病患者中调查四肢输液指数 (PI) 和血液乳酸之间的相关性.
- 评估PI对神经病中微循环 perfusion 代谢障碍的预测价值.
- 建立一个潜在的微循环功能障碍早期预警指标.
主要方法:
- 在神经重症监护室 (NICU) 进行前性观察性研究.
- 测量了44名神经病患者的血压,心率,四肢PI和动脉血液乳酸.
- 使用的接收机运营商特征 (ROC) 曲线分析以评估预测值.
主要成果:
- 双边食指或双边脚之间的PI没有显著差异.
- 脚的PI明显低于同一侧的食指.
- 所有四个四肢的PI都显示出与动脉血液乳酸的显著负相关性.
- ROC分析表明,PI可以预测微循环 perfusion 代谢障碍 (AUC范围:0.718-0.767).
- 右食指PI截止值为2.46,显示了70.4%的灵敏度和75.4%的特异性.
结论:
- 单侧上肢和下肢PI测量显示下脚PI与食指PI相比.
- 四肢PI和动脉血液乳酸之间存在显著的负相关性.
- 在神经病患者中,PI作为微循环 perfusion 代谢障碍的有价值预测指标.
- 2.46的PI切断线被确定用于预测这种疾病.
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