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肥胖症,肥胖症和胃肠道癌症,以及其他疾病
Yuntao Zou1, Capecomorin S Pitchumoni1
1Department of Medicine, Saint Peter's University Hospital, 125 Andover DR, Kendall Park, New Brunswick, NJ 08901, USA.
Disease-a-month : DM
|June 12, 2023
概括
肥胖是一个日益严重的全球健康问题,与代谢综合征和各种癌症有关. 早期检测和个性化护理考虑BMI以外的因素对于预防和管理至关重要.
科学领域:
- 公共卫生 公共卫生
- 内分泌学 在内分泌学.
- 在瘤学瘤学.
背景情况:
- 肥胖是一个全球性流行病,与代谢综合征,2型糖尿病,高血压,中风和许多癌症有关.
- 它是胃肠道 (GI) 和非胃肠道癌症的重要危险因素.
- 肥胖是异质的,内脏脂肪组织 (VAT) 在慢性炎症和胰岛素抵抗中发挥着关键的内分泌作用.
研究的目的:
- 突出全球肥胖率的上升,作为一种需要早期发现和护理的疾病.
- 讨论肥胖与包括胃肠道恶性瘤在内的各种癌症之间的病因联系.
- 强调需要对超出身体质量指数 (BMI) 的肥胖症进行细微的临床评估.
主要方法:
- 关于肥胖及其健康后果的流行病学和临床研究的审查.
- 分析与超重和肥胖有关的癌症发病率数据.
- 讨论临床指南和仅使用BMI的局限性.
主要成果:
- 肥胖与几种癌症的发病率增加有关,特别是胃肠道癌症.
- 超重和肥胖在很大程度上是可以预防的癌症原因.
- 代谢肥胖的正常体重个体和代谢健康的肥胖个体存在独特的临床挑战.
结论:
- 对BMI进行批判性评估,考虑种族和身体习惯,对于评估与肥胖相关的风险至关重要.
- 预防和管理超重和肥胖应该是公共卫生的优先事项,并纳入常规医疗保健.
- 政策变化支持更健康的食物和体育活动环境对于打击肥胖流行病至关重要.
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