了解在初级保健中患有精神疾病的患者的药物安全挑战:范围审查
Matthew J Ayre1, Penny J Lewis2,3,4, Richard N Keers2,3,5
1Division of Pharmacy and Optometry, School of Health Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK. matthew.ayre@manchester.ac.uk.
BMC psychiatry
|June 12, 2023
概括
在初级保健中,精神疾病患者的药物安全性是分散的. 研究突出了不遵守和处方问题,强调需要有针对性的干预措施来改善患者的治疗结果.
科学领域:
- 药物监督 药物监督 药物监督
- 初级医疗保健医学 一级医疗保健医学
- 心理健康研究 心理健康研究
背景情况:
- 药物安全是全球医疗保健的优先事项,特别是在精神疾病患者中.
- 大多数精神疾病患者在初级环境中接受护理,但药物安全挑战仍然不明朗.
研究的目的:
- 系统地审查和综合现有关于初级保健中精神疾病患者药物安全挑战的研究.
- 确定常见的与毒品有关的问题 (DRP),其原因,并评估干预措施.
主要方法:
- 在六个电子数据库,谷歌学者和参考列表中进行了全面的文献搜索 (2000年1月至2023年1月).
- 包括报告流行病学,病因学或与精神疾病初级保健患者药物安全相关的干预措施的研究.
- 使用药物相关问题 (DRP) 框架对药物安全挑战进行了分类.
主要成果:
- 包括79项研究,主要来自美国 (41.8%).
- 不遵守是最受调查的DRP (78.5%),与患者相关的因素是最常见的原因 (92.0%).
- 干预措施,通常由专业药剂师领导,主要集中在改善遵守,大多数报告的积极结果.
结论:
- 患有精神疾病的患者在初级保健中面临显著的DRP,目前的研究往往侧重于特定人群的不遵守和处方问题.
- 需要进一步的研究,以了解可预防的药物使用事故的原因.
- 针对性干预对于在初级保健机构内增强这一患者群体的药物安全至关重要.
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