通过基于风险因子的多基因评分,改善了膝关节骨关节炎风险的遗传预测

Yugo Morita1,2, Yoichiro Kamatani2, Hiromu Ito3,4

  • 1Department of Orthopedic Surgery, Kyoto University Graduate School of Medicine, Kyoto, Japan.

PubMed
概括

在日本人的膝关节骨关节炎 (OA) 开发多基因风险评分 (PRS) 显著提高了预测准确性. 这种多特征的PRS利用多种人群数据,为评估不同人群中OA风险提供了一个有前途的工具.

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