纤维细胞生长因子21 (FGF21) 通过转录因子EB (TFEB) 调节的脂质缩来减弱塔克罗利斯诱导的肝脂积累

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Ferritinophagy: Assessing the Selective Degradation of Iron by Autophagy in Human Fibroblasts
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Zhensheng Zhang1,2,3,4,5, Li Xu6,3,4,5, Xun Qiu1,2,3,4,5

  • 1Zhejiang University School of Medicine, Hangzhou 310058, China.

Journal of Zhejiang University. Science. B
|June 13, 2023
PubMed
概括

塔克罗利 (TAC) 通过降低纤维细胞生长因子21 (FGF21) 的调节,导致高脂血症,从而损害了自-溶解体通路. 再组合的FGF21蛋白通过增强自逆转这种脂质积累和高甘油三血症.

关键词:
自自是一种自的过程.纤维细胞生长因子21 (FGF21)脂质 脂质 是一种脂质性消化 (Lipophagy) 是一种消化方式.lysosome 是一个溶解体.塔克罗利慕斯可以使用.转录因子EB (TFEB) 是一个转录因子.

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