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预后营养指数 (PNI) 作为老年患者中COPD恶化的潜在预后工具

Eiko Suzuki¹, Naoko Kawata¹, Ayako Shimada^1,2

¹Department of Respirology, Graduate School of Medicine, Chiba University, Chiba-shi, Chiba, 260-8677, Japan.

International journal of chronic obstructive pulmonary disease

|June 13, 2023

概括

通过预后营养指数 (PNI) 表示的营养状况和COPD评估测试 (CAT) 分数可以帮助预测老年COPD患者的恶化. 结合CAT和PNI可以提高这些个体的预后准确性.

科学领域:

老年学是一门学科.
肺部病理学肺部病理学
临床营养学临床营养学

背景情况:

慢性阻塞性肺病 (COPD) 恶化严重影响生活质量和预后.
营养指数正在成为慢性疾病的关键预后因素.
老年COPD患者营养指标的预后价值仍未得到充分研究.

研究的目的:

研究COPD老年患者的营养指标和预后之间的关系.
评估预后营养指数 (PNI) 对老年人COPD恶化的预测价值.

主要方法:

91名COPD患者接受了COPD评估测试 (CAT),螺旋测量,血液测试和MDCT.
患者被分为<75岁 (n=57) 和≥75岁 (n=34) 的年龄组.
预后营养指数 (PNI) 是使用血清白蛋白和淋巴细胞总数计算的.

主要成果:

在PNI和CAT,FEV1%pred或LAV%之间没有发现显著的相关性.
患有恶化症状的老年患者与没有恶化症状的老年患者相比,CAT和PNI的显著差异 (p=0.008,p=0.004).
一个CAT和PNI的综合分析模型显著改善了老年人恶化预测 (p=0.0068).

结论:

慢性肺炎评估测试 (CAT) 和预后营养指数 (PNI) 与老年患者的慢性肺炎恶化风险有关.
对CAT和PNI的综合评估为老年人中COPD管理提供了潜在的有价值的预后工具.

关键词:

慢性阻塞性肺病慢性阻塞性肺病恶化的恶化.预后营养指数的预后.

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