在妊娠前中评估胎儿心脏功能:严重程度或蛋白尿会影响胎儿心脏功能吗?
Derya Uyan Hendem1, Deniz Oluklu1, Dilek Menekse Beser1
1Department of Obstetrics and Gynecology, Division of Perinatology, Turkish Ministry of Health Ankara City Hospital, Ankara, Turkey.
孕前会损害胎儿的心脏功能,影响心和腹参数. 组织多普勒成像检测到这些亚临床变化,这些变化在蛋白尿水平较高时更为严重.
科学领域:
- 心脏病学 心脏病学
- 产科 产科 产科 产科 产科
- 胎儿医学 胎儿医学
背景情况:
- 孕前是一种严重的妊娠并发症.
- 胎儿的心脏功能可能会受到母亲的条件的影响.
研究的目的:
- 在孕前症中比较胎儿心脏功能与对照.
- 评估蛋白尿严重程度对胎儿心脏功能的影响.
主要方法:
- 对96名孕妇进行的前性病例对照研究 (48名孕前,48名对照).
- 使用脉冲波多普勒,M模式和组织多普勒成像 (32-34周怀孕).
- 分析的子组根据孕前的严重程度和蛋白尿水平 (>3g/24h vs. <3g/24h).
主要成果:
- 孕前症组显示胎儿的透析功能减弱 (心膜/三 E,A,E',A'值;异体积度放松时间增加).
- 孕前症组表现出缩功能下降 (环状平面缩外流,S'值).
- 严重的孕前病例比轻度病例有较低的三 E 值.
结论:
- 孕前可以诱导胎儿心脏的亚临床缩和腹缩变化.
- 组织多普勒成像提供了对这些早期功能变化的敏感检测.
- 双管管管直通功能障碍在患有蛋白尿 >3g/24h 的孕前胎儿中更加明显.
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