与衰老相关的胃肠道疾病降低了丰富的全麦麦面包中的植物醇的生物可访问性:in vitro静态消化
Diego Miedes1, Mussa Makran1, Antonio Cilla1
1Nutrition and Food Science Area, Faculty of Pharmacy, University of Valencia, Av. Vicent Andrés Estellés s/n, 46100 Burjassot, Valencia, Spain. Antonio.cilla@uv.es.
Food & function
|June 13, 2023
概括
在全麦面包中的植物醇 (PS) 有助于降低胆固醇. 在老年人中,它们的吸收率较低,但由于其营养价值,面包仍然有益.
科学领域:
- 营养科学 营养科学
- 食品科学 食品科学 食品科学
- 心血管健康 心血管健康
背景情况:
- 预防心血管疾病对于老年人来说至关重要.
- 植物固醇 (PS) 以其降胆固醇效应而闻名.
- 强化食品,如全麦麦面包 (WRB),提供一种饮食方法来增强PS摄入量.
研究的目的:
- 为了识别和量化PS丰富的全麦麦面包 (WRB) 中的植物固醇 (PS).
- 通过模拟静态消化模型评估WRB中PS的生物可访问性.
- 为了比较老年人和成人胃肠道模型之间的PS生物可访问性.
主要方法:
- 在富含PS的WRB中识别和量化九种不同的植物固醇 (PS).
- 在适应的胃肠道条件下模拟静态消化,以评估PS的生物可访问性.
- 老年人和成年人消化模型之间的生物可访问性数据的比较.
主要成果:
- 在WRB中,总计确定了2.18g/100g的PS.
- 与成人模型 (20.3%) 相比,PS生物可访问性在老年模型 (11.2%) 中明显较低.
- 当仅适应胃阶段时,没有发现生物可访问性的显著差异.
结论:
- 虽然PS的生物可访问性在老年人中降低,但由于其整体营养特征,WRB的消费仍然可以促进心血管健康.
- 这些发现凸显了进一步进行体内研究的必要性,以证实PS丰富食品在老年人群中的益处.
- 在老年人中优化PS的输送和吸收需要进一步的研究.
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