微型神经植入物用于局部化和可控制的药物输送到大脑
Xiaotong Zhao1,2, Maosen Deng1,2, Jun Wang3
1School of Biomedical Engineering, Shenzhen Campus of Sun Yat-sen University, Shenzhen 518107, China. lizhe28@mail.sysu.edu.cn.
Journal of materials chemistry. B
|June 13, 2023
概括
微型神经植入物提供精确的,最少的侵入性药物输送到大脑,克服血脑屏障. 这些先进的设备利用新技术针对性地治疗大脑疾病.
科学领域:
- 生物医学工程 生物医学工程
- 神经科学是一个神经科学.
- 药物输送系统 药物输送系统
背景情况:
- 血脑屏障对有效向大脑输送药物构成了重大挑战.
- 系统性药物管理往往缺乏治疗神经系统疾病所需的特异性.
- 局部化,最少侵入性的方法对于针对性脑疾病治疗至关重要.
研究的目的:
- 审查最近在微型神经植入物中取得的进展,以便在大脑中准确和可控制的药物输送.
- 突出创新技术和材料,使最小侵入性脑药物输送成为可能.
- 为了强调这些植入物治疗大脑疾病的潜力.
主要方法:
- 关于微型神经植入物用于大脑药物输送的当前文献的综述.
- 对植入物制造中使用的技术和材料的分析.
- 讨论植入器的功能,包括外部和集成的微流体.
主要成果:
- 开发各种各样的创意神经植入物和用于大脑药物输送的平台.
- 在小型化,多功能药物输送植入物中证明了功能性的演示.
- 在植入物设计中整合先进的工程技术和新兴材料.
结论:
- 微型神经植入物代表了针对性和最小侵入性脑药物输送的重大进步.
- 在工程和材料科学领域的持续创新将推动治疗大脑疾病的进步.
- 这些植入物为有效的神经治疗提供了一个有希望的未来.
相关概念视频
01:29Drug Delivery: Parenteral Route
644
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
644
01:14Brain Imaging
264
Brain imaging technologies provide critical insights into both the structure and function of the human brain, enabling medical professionals and researchers to diagnose, study, and treat neurological disorders or psychiatric disorders more effectively.
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
These technologies include computerized axial tomography (CAT or CT scans), positron-emission tomography (PET scans), magnetic resonance imaging (MRI), functional magnetic resonance imaging (fMRI), and Transcranial Magnetic...
264