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Updated: Jul 26, 2025

Establishment of Cancer Stem Cell Cultures from Human Conventional Osteosarcoma
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在康斯塔丁-M和OSM-受体中,MAPK的前激活会诱导可分离的干状和介酶体程序

Kelsey L Polak1, Ilaria Tamagno1, Neetha Parameswaran1

  • 1Department of Pathology and Case Comprehensive Cancer Center, Case Western Reserve University Cleveland, Ohio.

Molecular cancer research : MCR
|June 13, 2023
PubMed
概括

昂哥斯塔丁-M (OSM) 通过激活MAPK信号来驱动胰腺癌干细胞和凝胺耐药性. 抑制这种OSM-OSMR-MAPK通路为侵袭性胰腺管腺癌 (PDAC) 提供了一种新的治疗策略.

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