含无氧化物的环开放共聚化与环氧化物作为功能聚合物的受控平台
Fernando Vidal1, Sevven Smith1, Charlotte K Williams1
1Department of Chemistry, Chemical Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, U.K.
Journal of the American Chemical Society
|June 13, 2023
概括
研究人员开发了一种使用受控环开放共聚化制造功能化可降解的新方法. 这种多功能技术允许可调节的聚合物结构和功能,使自组装纳米粒子和生物成像中的应用成为可能.
科学领域:
- 聚合物化学
- 材料科学
- 有机合成
背景情况:
- 功能化聚合物对于光电子,生物学和医学至关重要.
- 开发用于功能化和可降解聚合物的方法对于需要散射的应用,如自组装纳米结构和生物成像至关重要.
- 目前生产这种聚合物的方法有限.
研究的目的:
- 开发一种可控环开合聚合 (ROCOP) 方法来合成功能化和可降解的聚合物.
- 探索这些新型聚合物的结构多样性,特性和潜在应用.
主要方法:
- 用各种环氧化物对乙烯化物的受控环开合聚合 (ROCOP).
- 使用有机金属复合物 (Zn{II}Mg{II},Al{III}K{I}) 或基基的催化.
- 用酸/酸盐去保护乙烯,用于功能化的Pd (II) 催化交叉合,以及两性聚合物的合成.
主要成果:
- 控制良好的聚合物产生可调节结构的聚合物 (AB,ABA块),分子质量 (9.440 kg/mol) 和功能 (,酸,酸盐,光组).
- 由此产生的聚合物具有较高的玻璃过渡温度 (81224 °C) 和良好的热稳定性 (285322 °C).
- 在水中自组装的光纳米粒子 (40纳米直径) 的合成.
结论:
- 开发的ROCOP方法为制造可降解,精确定义和功能性的含聚合物提供了多功能平台.
- 聚合物结构,成分和负荷的调节能力为先进材料开辟了道路.
- 这些聚合物适用于自组装纳米结构,动态网络和生物成像.
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