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使用可测量的残留疾病来优化AML,ALL和慢性髓性白血病的管理

Simone E Dekker¹, Delphine Rea^2,3, Jean-Michel Cayuela^2,4

¹Department of Medicine, Oregon Health & Science University, Portland, OR.

American Society of Clinical Oncology educational book. American Society of Clinical Oncology. Annual Meeting

|June 13, 2023

概括

可测量的残留疾病 (MRD) 监测对于管理白血病至关重要. 本综述涵盖了MRD评估方法,临床应用和急性髓性白血病 (AML),急性淋巴细胞白血病 (ALL) 和慢性髓性白血病 (CML) 的未来方向.

科学领域:

血液学血液学血液学
在瘤学瘤学.
分子诊断学分子诊断

背景情况:

可测量的残留疾病 (MRD) 监测是各种血液恶性瘤管理的关键组成部分.
了解MRD的作用对于优化治疗策略和预测白血病患者的结果至关重要.

结论:

优化MRD评估和将其纳入临床实践对于改善白血病管理至关重要.
需要进一步的研究来应对当前的挑战,并在全球范围内标准化MRD的使用.
患者应被告知MRD对其疾病状况和治疗过程的重要性.

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