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Updated: Jul 26, 2025

Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry
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Synthesis of Protein Bioconjugates via Cysteine-maleimide Chemistry

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在中性pH下在蛋白质表面上选择性安装ArylDiazonium,使用Maleimide功能化的Triazabutadiene

Nicholas D J Yates1, Natasha E Hatton1, Martin A Fascione1

  • 1Department of Chemistry, University of York Heslington, York, YO10 5DD, UK.

Chembiochem : a European journal of chemical biology
|June 13, 2023
PubMed
概括

研究人员开发了一种新型的triazabutadiene用于选择性蛋白质修饰. 这种试剂可以在温和的,生物相关的条件下产生酸,用于像光开关和药物合物这样的应用.

关键词:
亚化合物 是一种亚化合物.光解是一种光学分析.保护群体保护群体蛋白质的修改 蛋白质的修改

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