在不同受孕率的公牛中,精子头形态学和染色质变化发生了变化
José Andrés Nivia Riveros1, Isabelle Cristina Pereira1, Ana Carolina Bahia Teixeira1
1Department of Veterinary Clinics and Surgery, Veterinary School, Universidade Federal de Minas Gerais (UFMG), Belo Horizonte, MG 31270-901, Brazil.
Animal reproduction science
|June 13, 2023
概括
精液质量超出了基本参数. 精子头形状和DNA完整性,而不仅仅是运动性,在定时人工授精 (AI) 中影响受孕率.
科学领域:
- 生殖生物学 生殖生物学
- 动物科学 动物科学
- 兽医医学 兽医医学 兽医医学
背景情况:
- 定时人工授精 (AI) 对于牛的繁殖至关重要.
- 传统的精液质量参数并不总能预测现场受孕率.
- 精子头形态学和染色质完整性是生育能力的新兴因素.
研究的目的:
- 为了研究 sire 怀孕率 (CRs) 和精液质量之间的关系.
- 分析与CRs相关的精子头形态和染色质变化.
- 确定用于定时人工智能的公牛生育能力的新型指标.
主要方法:
- 收集了6只安格斯公牛的精液,用于890只内罗尔牛的定时AI.
- 评估的常规精液参数:运动性,度和形态.
- 使用先进技术评估精子头形态测量和染色质变化.
主要成果:
- 整体受孕率为49%,公牛之间存在显著差异.
- 怀孕率较低的公牛表现出明显的精子头形态特征和/或增加的染色质变化.
- 传统的精液质量评估没有检测到这些差异.
结论:
- 精子头形态学和染色质变化可能会解释不同男性怀孕率的变化.
- 传统的精液分析可能不足以预测田间生育能力.
- 需要进一步的研究来证实染色质改变对生育能力的影响.
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