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Updated: Jul 26, 2025

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通过脂质过氧化,用活性碳基物种对氨酸的碳化,会诱导氨酸活性部位的局部结构变化

Rafael Pineda-Alemán1, Antistio Alviz-Amador2, Rodrigo Galindo-Murillo3

  • 1Analytical Chemistry and Biomedicine Group, Medicine Faculty, University of Cartagena, Cartagena, Colombia.

Journal of molecular graphics & modelling
|June 13, 2023
PubMed
概括

反应性碳类物种 (RCS) 修改了诸如铁素 (Trx) 等蛋白质,影响了细胞健康. 分子动力学模拟显示,这些修改导致局部结构变化而不是全球变化.

关键词:
分子动态模拟的分子动态模拟.蛋白质碳基化蛋白质的碳基化.有反应性碳烯物种的反应性碳烯物种.结构性影响 结构性影响

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