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免疫遗传多态性预测了接受PD-1/PD-L1阻断治疗的瘤患者的治疗疗效和生存结果

Zhaodan Xin1, Liting You2, Jin Li1

  • 1Department of Laboratory Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan Province 610041, PR China.

International immunopharmacology
|June 13, 2023
PubMed
概括

三种免疫遗传变异 (ATG7,CD274,TLR4) 预测了对PD-1/PD-L1阻塞疗法的反应. 这些遗传变异可能表明瘤进展的风险增加和癌症患者的无进展生存率较差.

关键词:
免疫检查点抑制剂 免疫检查点抑制剂免疫遗传变体 免疫遗传变体没有进展的生存率.治疗生物标志物治疗生物标志物

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